Chlorphenoxamine
Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]
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Routes of administration | Oral, topical |
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Bioavailability | Well absorbed |
Metabolism | Likely hepatic |
Excretion | Renal |
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ECHA InfoCard | 100.115.538 |
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Formula | C18H22ClNO |
Molar mass | 303.826 g/mol g·mol−1 |
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References
- Bazex, A.; Dupre, A.; Christol, B. (1963). "Trial treatment of urticaria with chlorphenoxamine". Clinique (Paris, France). 58: 447–450. PMID 13967113.
- Uldall, P. R.; Walton, J. N.; Newell, D. J. (1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–1652. doi:10.1136/bmj.1.5240.1649. PMC 1954253. PMID 13779077.
- H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).
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See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake inhibitors |
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