Chlorphenoxamine

Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]

Chlorphenoxamine
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, topical
ATC code
Pharmacokinetic data
BioavailabilityWell absorbed
MetabolismLikely hepatic
ExcretionRenal
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.115.538
Chemical and physical data
FormulaC18H22ClNO
Molar mass303.826 g/mol g·mol−1
3D model (JSmol)
 NY (what is this?)  (verify)

References

  1. Bazex, A.; Dupre, A.; Christol, B. (1963). "Trial treatment of urticaria with chlorphenoxamine". Clinique (Paris, France). 58: 447–450. PMID 13967113.
  2. Uldall, P. R.; Walton, J. N.; Newell, D. J. (1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–1652. doi:10.1136/bmj.1.5240.1649. PMC 1954253. PMID 13779077.
  3. H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).


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