Center-surround antagonism

Center-surround antagonism refers to antagonistic interactions between center and surround regions of the receptive fields of photoreceptor cells in the retina. Center surround antagonism enables edge detection and contrast enhancement within the visual cortex.

References

Westheimer, Gerald (2004). "Center-surround antagonism in spatial vision: Retinal or cortical locus?" (PDF). Vision Research. 44 (21): 2457–65. doi:10.1016/j.visres.2004.05.014. PMID 15358081.

Pharmacomodulation

Types

♦ Enzyme: Inducer
Inhibitor

♦ Ion channel: Opener
Blocker

♦ Transporter [Reuptake vs Efflux]: Enhancer (RE)
Inhibitor (RI)
Releaser (RA)

♦ Miscellaneous: Precursor
Cofactor

Classes

Enzyme

see Enzyme inhibition

See Ion channel modulators

Receptor &
transporter

Adrenergic	Adrenergic receptor agonist (α β (1 2)) Adrenergic receptor antagonist (α (1 2) β) Norepinephrine reuptake inhibitor (NRI)
Dopaminergic	Dopamine receptor agonist Dopamine receptor antagonist Dopamine reuptake inhibitor (DRI)
Histaminergic	Histamine receptor agonist Histamine receptor antagonist (H₁ H₂ H₃)
Serotonergic	Serotonin receptor agonist Serotonin receptor antagonist (5-HT₃) Serotonin reuptake inhibitor (SRI)

AA

GABAergic	GABA receptor agonist GABA receptor antagonist GABA reuptake inhibitor (GRI)
Glutamatergic	Glutamate receptor agonist (AMPA) Glutamate receptor antagonist (NMDA) Glutamate reuptake inhibitor

Cannabinoidergic

Cannabinoid receptor agonist
Cannabinoid receptor antagonist
Endocannabinoid enhancer (eCBE)
Endocannabinoid reuptake inhibitor (eCBRI)

Other

Miscellaneous

Cofactor (see Enzyme cofactors)
Precursor (see Amino acids)

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