Cathartic

In medicine, a cathartic is a substance that accelerates defecation. This is in contrast to a laxative, which is a substance that eases defecation, usually by softening feces.[1] It is possible for a substance to be both a laxative and a cathartic. However, agents such as psyllium seed husks increase the bulk of the feces.[2]

Cathartics such as sorbitol, magnesium citrate, magnesium sulfate, or sodium sulfate were previously used as a form of gastrointestinal decontamination following poisoning via ingestion. They are no longer routinely recommended for poisonings.[3] High-dose cathartics may be an effective means of ridding the lower gastrointestinal tract of toxins; however, they carry a risk of electrolyte imbalances and dehydration.[4] Catharsis can be an effect of pesticide poisonings, such as with elemental sulfur.[5]

References
  1. Cathartics at the US National Library of Medicine Medical Subject Headings (MeSH)
  2. The MSDS HyperGlossary: Catharsis
  3. American Academy Of Clinical Toxico; European Association Of Poisons Cen (2004). "Position paper: cathartics". Journal of Toxicology. Clinical Toxicology. 42 (3): 243–53. doi:10.1081/CLT-120039801. PMID 15362590.
  4. Tamara McGregor; et al. (2009). "Evaluation and management of common childhood poisonings". Am Fam Physician. 79 (5): 397–403. PMID 19275069.
  5. Roberts, James R.; Reigart, J. Routt (2013). "Other Insecticides and Acaracides" (PDF). Recognition and Management of Pesticide Poisonings (6th ed.). Washington DC: Office of Pesticide Programs, U.S. Environmental Protection Agency. p. 93.


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