Blood gas tension
Blood gas tension refers to the partial pressure of gases in blood. There are several significant purposes for measuring gas tension; the most common gas tensions measured are oxygen tension (PxO2), the carbon dioxide tension (PxCO2) and carbon monoxide tension (PxCO). The subscript x in each symbol represents the source of the gas being measured; "a" meaning arterial, "A" being alveolar, "v" being venous, "c" being capillary. Blood gas tests (such as arterial blood gas tests) measure these partial pressures.
- Arterial blood oxygen tension (normal)
PaO2 – Partial pressure of oxygen at sea level (760 mmHg in the atmosphere) in arterial blood is between 75 mmHg and 100 mmHg.
- Venous blood oxygen tension (normal)
PvO2 – Oxygen tension in venous blood at sea level is between 30 mmHg and 40 mmHg.
Carbon dioxide tension
- Arterial blood carbon dioxide tension
PaCO2 – Partial pressure of carbon dioxide at sea level in arterial blood is between 35 mmHg and 45 mmHg.
- Venous blood carbon dioxide tension
Carbon monoxide tension
- Arterial carbon monoxide tension (normal)
PaCO – Partial pressure of CO at sea level in arterial blood is approximately 0.02. It can be slightly higher in smokers and people living in dense urban areas.
The partial pressure of gas in blood is significant because it is directly related to ventilation and oxygenation. When used alongside the pH balance of the blood, the PaCO2 and HCO3 (and Lactate) suggest to the health care practitioner which interventions, if any, should be made.
The constant, 1.36, is the amount of oxygen (ml at 1 atmosphere) bound per gram of hemoglobin. The exact value of this constant varies from 1.34 to 1.39, depending on the reference and the way it is derived. The constant 0.0031 represents the amount of oxygen dissolved in plasma. The dissolved-oxygen term is generally small relative to the term for hemoglobin-bound oxygen, but becomes significant at very high PaO2 (as in a hyperbaric chamber) or in severe anemia.
- Alveolar air equation
- Fick's laws of diffusion
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