Avibirnavirus
Avibirnavirus is a genus of viruses in the family Birnaviridae.[2] Young chickens and other fowl serve as natural hosts. There are currently only one species in this genus: the type species Infectious bursal disease virus. Diseases associated with this genus include: IBDV causes severe inflammation of the bursa of fabricius. The disease causes considerable morbidity and mortality in an acute form or as a consequence of severe immunosuppression provoked by the destruction of immature B-lymphocytes within the bursa of fabricius.[3][4]
Avibirnavirus | |
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Virus classification ![]() | |
(unranked): | Virus |
Realm: | Riboviria |
Phylum: | incertae sedis |
Family: | Birnaviridae |
Genus: | Avibirnavirus |
Type species | |
*Infectious bursal disease virus | |
Species[1] | |
|
Structure
Viruses in Avibirnavirus are non-enveloped, with icosahedral and Single-shelled geometries, and T=13 symmetry. The diameter is around 70 nm. Genomes are linear and segmented, around 15.2.9-3kb in length. The genome codes for 5 proteins.[3][4]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Avibirnavirus | Icosahedral | T=13 | Non-enveloped | Linear | Segmented |
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the double-stranded RNA virus replication model. Double-stranded rna virus transcription is the method of transcription. Young chickens and other fowl serve as the natural host. Transmission routes are contamination.[3][4]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Avibirnavirus | Birds | None | Cell receptor endocytosis | Budding | Cytoplasm | Cytoplasm | Contact |
References
- "Virus Taxonomy: 2018b Release" (html). International Committee on Taxonomy of Viruses (ICTV). March 2019. Retrieved 8 November 2019.
- Delmas, B; Attoui, H; Ghosh, S; Malik, YS; Mundt, E; Vakharia, VN; Ictv Report, Consortium (January 2019). "ICTV virus taxonomy profile: Birnaviridae". The Journal of General Virology. 100 (1): 5–6. doi:10.1099/jgv.0.001185. PMID 30484762.
- "ICTV Report Birnaviridae".
- "Viral Zone". ExPASy. Retrieved 15 June 2015.