Atazanavir/cobicistat
Atazanavir/cobicistat (trade name Evotaz) is an antiretroviral medication used to treat and prevent HIV/AIDS. It is a fixed dose combination drug containing 300 mg of atazanavir and 150 mg of cobicistat.[1] Atazanavir is an HIV protease inhibitor and cobicistat blocks the body's metabolism of atazanavir by the enzyme CYP3A prolonging its effectiveness.
Combination of | |
---|---|
Atazanavir | HIV protease inhibitor |
Cobicistat | Cytochrome P450 (CYP3A) inhibitor |
Clinical data | |
Trade names | Evotaz |
Identifiers | |
KEGG |
It was approved by the Food and Drug Administration for use in United States in 2015.[2]
References
- "Evotaz Packing Insert" (PDF).
- "U.S. Food and Drug Administration Approves Bristol-Myers Squibb's Evotaz™ (atazanavir and cobicistat) for the Treatment of HIV-1 Infection in Adults" (Press release). Bristol-Myers Squibb.
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