Amur virus

Amur virus (AMRV) is a zoonotic negative-sense single-stranded RNA virus. It may be a member of the genus Orthohantavirus, but it has not be definitively classified as a species and may only be a strain.[1] It has been identified as a causative agent of hemorrhagic fever with renal syndrome.[2][3]

Amur virus
Virus classification
(unranked): Virus
Realm: Riboviria
Phylum: Negarnaviricota
Class: Ellioviricetes
Order: Bunyavirales
Family: Hantaviridae
Subfamily: Mammantavirinae
Genus: Orthohantavirus (?)
Virus:
Amur virus
Synonyms[1]

Genome

The complete genome sequence Amur virus has been isolated from a sample obtained from Apodemus peninsulae in Northeastern China.[3] AMRV strains from China and Far East and Soochong virus (SOOV) (especially SOO-1/2 strains from Northeastern Korea) were found to share high identities of nucleotide sequences and were monophyletic distinct from Apodemus agrarius HTNV. Two genetic sublineages of SOOV exist, but findings suggest that AMRV and SOOV are different strains of the same hantavirus.[4]

Reservoir

The virus is reported to be carried by Korean field mice (Apodemus peninsulae) in the Far East of Russia, China, and Korea.[4]

See also

References
  1. Plyusnin, A.; Beaty, B.J.; Elliott, R.M.; Goldbach, R.; Kormelink, R.; Lundkvist, Å.; Schmaljohn, C.S.; Tesh, R.B (2011). "ICTV 9th Report (2011) Bunyaviridae" (html). International Committee on Taxonomy of Viruses (ICTV). Retrieved 17 February 2019. List of other related viruses which may be members of the genus Hantavirus but have not been approved as species Amur/Soochong virus {Apodemus peninsulae} [L: DQ056292; M: AY675353; S:AY675349] (ASV)
  2. Lokugamage K, Kariwa H, Lokugamage N, Miyamoto H, Iwasa M, Hagiya T, Araki K, Tachi A, Mizutani T, Yoshimatsu K, Arikawa J, Takashima I (2004). "Genetic and antigenic characterization of the Amur virus associated with hemorrhagic fever with renal syndrome". Virus Res. 101 (2): 127–34. doi:10.1016/j.virusres.2003.12.031. PMID 15041180.
  3. Yao LS, Zhao H, Shao LJ, Liu YX, Zhang XL, Wang J, Deng YQ, Li XF, Hu KX, Qin CF, Xu BL (2012). "Complete genome sequence of an amur virus isolated from Apodemus peninsulae in Northeastern China". J. Virol. 86 (24): 13816–7. doi:10.1128/JVI.02586-12. PMC 3503078. PMID 23166234.
  4. Jiang JF, Zhang WY, Wu XM, Zhang PH, Cao WC (2007). "Soochong virus and Amur virus might be the same entities of hantavirus". J. Med. Virol. 79 (11): 1792–5. doi:10.1002/jmv.20957. PMID 17854038.
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