3,3'-Diiodothyronine
3,3'-Diiodothyronine, also known as 3,3'-T2, is a metabolite of thyroid hormone.
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| IUPAC name
2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid | |
| Other names
O-(4-Hydroxy-3-iodophenyl)-3-iodotyrosine | |
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| MeSH | 3,3'-diiodothyronine |
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| Properties | |
Chemical formula |
C15H13I2NO4 |
| Molar mass | 525.077 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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It is formed from the breakdown of triiodothyronine. Levels can be affected in certain disease states.[1]
Reactions
Synthesis of T2 from T3, and from reverse T3
References
- Pinna G; Hiedra L; Meinhold H; et al. (September 1998). "3,3'-Diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors and of healthy subjects during acute stress". J. Clin. Endocrinol. Metab. 83 (9): 3071–7. doi:10.1210/jc.83.9.3071. PMID 9745405.
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